Using an animal model to predict the effective human dose for oral multiple sclerosis drugs

The objective of this study was to determine the potential usefulness of an animal model to predict the appropriate dose of newly developed drugs for treating relapsing remitting multiple sclerosis (RRMS). Conversion of the lowest effective dose (LEffD) for mice and rats in the experimental autoimmu...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Yu, Zhiheng, Wang, Ziyu, Waubant, Emmanuelle L., Zhai, Suodi, Benet, Leslie Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014696/
https://www.ncbi.nlm.nih.gov/pubmed/36419359
http://dx.doi.org/10.1111/cts.13458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014696/
https://www.ncbi.nlm.nih.gov/pubmed/36419359
http://dx.doi.org/10.1111/cts.13458

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