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The randomized, single‐ and multiple‐ ascending dose studies of the safety, tolerability, pharmacokinetics of CSPCHA115 in healthy Chinese subjects

CSPCHA115 is a highly selective and potent antagonist of chemoattractant receptor‐homologous molecule expressed on TH2 cells (CRTH2). This study aimed to evaluate the pharmacokinetics (PKs), safety, and tolerability of single and multiple ascending doses of CSPCHA115 in Chinese healthy subjects. Two...

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Detalles Bibliográficos
Autores principales: Jing, Shan, Liu, Wenfang, Yang, Kexu, Lin, Yang, Yao, Xuekun, Sun, Guilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014699/
https://www.ncbi.nlm.nih.gov/pubmed/36495036
http://dx.doi.org/10.1111/cts.13455