The impact of genetic variability in urate transporters on oxypurinol pharmacokinetics

The genetic determinants of the allopurinol dose‐concentration relationship have not been extensively studied. We aimed to clarify what factors, including genetic variation in urate transporters, influence oxypurinol pharmacokinetics (PKs). A population PK model for oxypurinol was developed with NON...

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Detalles Bibliográficos
Autores principales: Hishe, Hailemichael Z., Stocker, Sophie L., Stamp, Lisa K., Dalbeth, Nicola, Merriman, Tony R., Phipps‐Green, Amanda, Wright, Daniel F. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014700/
https://www.ncbi.nlm.nih.gov/pubmed/36398357
http://dx.doi.org/10.1111/cts.13460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014700/
https://www.ncbi.nlm.nih.gov/pubmed/36398357
http://dx.doi.org/10.1111/cts.13460

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