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Dormant cancer cells: programmed quiescence, senescence, or both?

Metastasis is the overwhelming driver of cancer mortality, accounting for the majority of cancer deaths. Many patients present with metastatic relapse years after eradication of the primary lesion. Disseminated cancer cells can undergo a durable proliferative arrest and lie dormant in secondary tiss...

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Detalles Bibliográficos
Autores principales: Truskowski, Kevin, Amend, Sarah R., Pienta, Kenneth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014758/
https://www.ncbi.nlm.nih.gov/pubmed/36598661
http://dx.doi.org/10.1007/s10555-022-10073-z