Visualizing genomic characteristics across an RNA-Seq based reference landscape of normal and neoplastic brain

In order to better understand the relationship between normal and neoplastic brain, we combined five publicly available large-scale datasets, correcting for batch effects and applying Uniform Manifold Approximation and Projection (UMAP) to RNA-Seq data. We assembled a reference Brain-UMAP including...

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Detalles Bibliográficos
Autores principales: Arora, Sonali, Szulzewsky, Frank, Jensen, Matt, Nuechterlein, Nicholas, Pattwell, Siobhan S., Holland, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014937/
https://www.ncbi.nlm.nih.gov/pubmed/36918656
http://dx.doi.org/10.1038/s41598-023-31180-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014937/
https://www.ncbi.nlm.nih.gov/pubmed/36918656
http://dx.doi.org/10.1038/s41598-023-31180-z

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