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Visualizing genomic characteristics across an RNA-Seq based reference landscape of normal and neoplastic brain
In order to better understand the relationship between normal and neoplastic brain, we combined five publicly available large-scale datasets, correcting for batch effects and applying Uniform Manifold Approximation and Projection (UMAP) to RNA-Seq data. We assembled a reference Brain-UMAP including...
Autores principales: | Arora, Sonali, Szulzewsky, Frank, Jensen, Matt, Nuechterlein, Nicholas, Pattwell, Siobhan S., Holland, Eric C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014937/ https://www.ncbi.nlm.nih.gov/pubmed/36918656 http://dx.doi.org/10.1038/s41598-023-31180-z |
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