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Mir125b-2 imprinted in human but not mouse brain regulates hippocampal function and circuit in mice

Genomic imprinting predominantly occurs in the placenta and brain. Few imprinted microRNAs have been identified in the brain, and their functional roles in the brain are not clear. Here we show paternal, but not maternal, expression of MIR125B2 in human but not mouse brain. Moreover, Mir125b-2(m)(−)...

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Detalles Bibliográficos
Autores principales: Chou, Ming-Yi, Cao, Xuhui, Hou, Kuan-Chu, Tsai, Meng-Han, Lee, Chih-Yu, Kuo, Meng-Fai, Wu, Vin-Cent, Huang, Hsin-Yi, Akbarian, Schahram, Chang, Sheng-Kai, Hu, Chung-Yi, Lin, Shu-Wha, Huang, Hsien-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014956/
https://www.ncbi.nlm.nih.gov/pubmed/36918719
http://dx.doi.org/10.1038/s42003-023-04655-y