Cargando…

UNC-43/CaMKII-triggered anterograde signals recruit GABA(A)Rs to mediate inhibitory synaptic transmission and plasticity at C. elegans NMJs

Disturbed inhibitory synaptic transmission has functional impacts on neurodevelopmental and psychiatric disorders. An essential mechanism for modulating inhibitory synaptic transmission is alteration of the postsynaptic abundance of GABA(A)Rs, which are stabilized by postsynaptic scaffold proteins a...

Descripción completa

Detalles Bibliográficos
Autores principales: Hao, Yue, Liu, Haowen, Zeng, Xian-Ting, Wang, Ya, Zeng, Wan-Xin, Qian, Kang-Ying, Li, Lei, Chi, Ming-Xuan, Gao, Shangbang, Hu, Zhitao, Tong, Xia-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015018/
https://www.ncbi.nlm.nih.gov/pubmed/36918518
http://dx.doi.org/10.1038/s41467-023-37137-0