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Downregulation of Sox8 mediates monosodium urate crystal-induced autophagic impairment of cartilage in gout arthritis

The deposition of monosodium urate (MSU) crystals in arthritic joints of gout seriously damages cartilage. This study aimed to investigate whether MSU crystal-induced cartilage impairment was related to autophagic signaling. mRNAs of cartilage from MSU-induced gouty arthritis rat model were sequence...

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Detalles Bibliográficos
Autores principales: Xiao, Lu, Lin, Shudian, Xu, WenChao, Sun, Erwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015026/
https://www.ncbi.nlm.nih.gov/pubmed/36918540
http://dx.doi.org/10.1038/s41420-023-01388-z