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Mechano-boosting nanomedicine antitumour efficacy by blocking the reticuloendothelial system with stiff nanogels

Nanomedicine has been developed for cancer therapy over several decades, while rapid clearance from blood circulation by reticuloendothelial system (RES) severely limits nanomedicine antitumour efficacy. We design a series of nanogels with distinctive stiffness and investigate how nanogel mechanical...

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Detalles Bibliográficos
Autores principales: Li, Zheng, Zhu, Yabo, Zeng, Haowen, Wang, Chong, Xu, Chen, Wang, Qiang, Wang, Huimin, Li, Shiyou, Chen, Jitang, Xiao, Chen, Yang, Xiangliang, Li, Zifu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015032/
https://www.ncbi.nlm.nih.gov/pubmed/36918575
http://dx.doi.org/10.1038/s41467-023-37150-3