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Efficacy of oral amantadine among patients hospitalised with COVID-19: A randomised, double-blind, placebo-controlled, multicentre study

BACKGROUND: Amantadine has been proposed as a treatment for COVID-19 because it shows anti-SARS-CoV-2 activity in vitro. However, to date, no controlled study has assessed the safety and efficacy of amantadine in COVID-19. RESEARCH QUESTION: Whether amantadine is effective and safe among patients wi...

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Detalles Bibliográficos
Autores principales: Barczyk, Adam, Czajkowska-Malinowska, Małgorzata, Farnik, Małgorzata, Barczyk, Marek, Boda, Łukasz, Cofta, Szczepan, Duława, Jan, Dyrbuś, Maciej, Harat, Rafał, Huk, Maciej, Kotecka, Sylwia, Nahorecki, Artur, Nasiłowski, Jacek, Naumnik, Wojciech, Przybylski, Grzegorz, Słaboń-Willand, Monika, Skoczyński, Szymon, Wita, Krystian, Zioło, Grzegorz, Kuna, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015090/
https://www.ncbi.nlm.nih.gov/pubmed/36931576
http://dx.doi.org/10.1016/j.rmed.2023.107198