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Apically-located P4-ATPase1-Lem1 complex internalizes phosphatidylserine and regulates motility-dependent invasion and egress in Toxoplasma gondii

The membrane asymmetry regulated by P4-ATPases is crucial for the functioning of eukaryotic cells. The underlying spatial translocation or flipping of specific lipids is usually assured by respective P4-ATPases coupled to conforming non-catalytic subunits. Our previous work has identified five P4-AT...

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Detalles Bibliográficos
Autores principales: Chen, Kai, Huang, Xiyu, Distler, Ute, Tenzer, Stefan, Günay-Esiyok, Özlem, Gupta, Nishith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015115/
https://www.ncbi.nlm.nih.gov/pubmed/36936814
http://dx.doi.org/10.1016/j.csbj.2023.02.032