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Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics
Elucidating enzyme–substrate relationships in posttranslational modification (PTM) networks is crucial for understanding signal transduction pathways but is technically difficult because enzyme–substrate interactions tend to be transient. Here, we demonstrate that TurboID-based proximity labeling (T...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015162/ https://www.ncbi.nlm.nih.gov/pubmed/36660928 http://dx.doi.org/10.1093/plcell/koad013 |