Activation of PPAR-γ prevents TERT-mediated pulmonary vascular remodeling in MCT-induced pulmonary hypertension

BACKGROUND: It has been demonstrated that elevated telomerase reverse transcriptase (TERT) expression or activity is implicated in pulmonary hypertension (PH). In addition, activation of peroxisome-proliferator-activated receptor γ (PPAR-γ) has been found to prevent PH progression. However, the mole...

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Detalles Bibliográficos
Autores principales: Hussain, Tafseel, Chai, Limin, Wang, Yan, Zhang, Qianqian, Wang, Jian, Shi, Wenhua, Wang, Qingting, Li, Manxiang, Xie, Xinming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015197/
https://www.ncbi.nlm.nih.gov/pubmed/36938425
http://dx.doi.org/10.1016/j.heliyon.2023.e14173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015197/
https://www.ncbi.nlm.nih.gov/pubmed/36938425
http://dx.doi.org/10.1016/j.heliyon.2023.e14173

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