BRD4‐PRC2 represses transcription of T‐helper 2‐specific negative regulators during T‐cell differentiation

BRD4 is a well‐recognized transcriptional activator, but how it regulates gene transcriptional repression in a cell type‐specific manner has remained elusive. In this study, we report that BRD4 works with Polycomb repressive complex 2 (PRC2) to repress transcriptional expression of the T‐helper 2 (T...

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Detalles Bibliográficos
Autores principales: Zhao, Li, Wang, Yiqi, Jaganathan, Anbalagan, Sun, Yifei, Ma, Ning, Li, Ning, Han, Xinye, Sun, Xueying, Yi, Huanfa, Fu, Shibo, Han, Fangbin, Li, Xue, Xiao, Kunhong, Walsh, Martin J, Zeng, Lei, Zhou, Ming‐Ming, Cheung, Ka Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015369/
https://www.ncbi.nlm.nih.gov/pubmed/36719036
http://dx.doi.org/10.15252/embj.2022111473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015369/
https://www.ncbi.nlm.nih.gov/pubmed/36719036
http://dx.doi.org/10.15252/embj.2022111473

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