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Structural Insights into Pseudomonas aeruginosa Exotoxin A–Elongation Factor 2 Interactions: A Molecular Dynamics Study

[Image: see text] Exotoxin A (ETA) is an extracellular secreted toxin and a single-chain polypeptide with A and B fragments that is produced by Pseudomonas aeruginosa. It catalyzes the ADP-ribosylation of a post-translationally modified histidine (diphthamide) on eukaryotic elongation factor 2 (eEF2...

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Detalles Bibliográficos
Autores principales: Gholami, Asma, Minai-Tehrani, Dariush, Mahdizadeh, Sayyed Jalil, Saenz-Mendez, Patricia, Eriksson, Leif A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015456/
https://www.ncbi.nlm.nih.gov/pubmed/36802593
http://dx.doi.org/10.1021/acs.jcim.3c00064