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Zn(II) to Ag(I) Swap in Rad50 Zinc Hook Domain Leads to Interprotein Complex Disruption through the Formation of Highly Stable Ag(x)(Cys)(y) Cores

[Image: see text] The widespread application of silver nanoparticles in medicinal and daily life products increases the exposure to Ag(I) of thiol-rich biological environments, which help control the cellular metallome. A displacement of native metal cofactors from their cognate protein sites is a k...

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Detalles Bibliográficos
Autores principales: Kerber, Olga, Tran, Józef, Misiaszek, Alicja, Chorążewska, Aleksandra, Bal, Wojciech, Krężel, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015552/
https://www.ncbi.nlm.nih.gov/pubmed/36863010
http://dx.doi.org/10.1021/acs.inorgchem.2c03767