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Zn(II) to Ag(I) Swap in Rad50 Zinc Hook Domain Leads to Interprotein Complex Disruption through the Formation of Highly Stable Ag(x)(Cys)(y) Cores
[Image: see text] The widespread application of silver nanoparticles in medicinal and daily life products increases the exposure to Ag(I) of thiol-rich biological environments, which help control the cellular metallome. A displacement of native metal cofactors from their cognate protein sites is a k...
Autores principales: | Kerber, Olga, Tran, Józef, Misiaszek, Alicja, Chorążewska, Aleksandra, Bal, Wojciech, Krężel, Artur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015552/ https://www.ncbi.nlm.nih.gov/pubmed/36863010 http://dx.doi.org/10.1021/acs.inorgchem.2c03767 |
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