Testicular impairment in Primary Adrenal Insufficiency caused by Nicotinamide Nucleotide Transhydrogenase (NNT) deficiency - a case report: implication of oxidative stress and importance of fertility preservation

INTRODUCTION: Nicotinamide nucleotide transhydrogenase (NNT) gene deficiency has recently been shown to be involved in Primary Adrenal Insufficiency (PAI). NNT encodes an inner mitochondrial membrane protein that produces large amounts of NADPH. NADPH is used in several biosynthesis pathways and the...

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Detalles Bibliográficos
Autores principales: Ferreux, Lucile, Boumerdassi, Yasmine, Dulioust, Emmanuel, Bertagna, Xavier, Roucher-Boulez, Florence, Bourdon, Mathilde, Thiounn, Nicolas, Patrat, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015661/
https://www.ncbi.nlm.nih.gov/pubmed/36918776
http://dx.doi.org/10.1186/s12610-022-00176-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015661/
https://www.ncbi.nlm.nih.gov/pubmed/36918776
http://dx.doi.org/10.1186/s12610-022-00176-6

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