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Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis

INTRODUCTION: Neutrophils are a pivotal cell type in the K/BxN mouse model of rheumatoid arthritis and play an essential role in the progression of the arthritis. They are readily activated by immune complexes (ICs) via their FcγRs to release IL-1β in addition to other cytokines, which are inducing...

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Detalles Bibliográficos
Autores principales: Almizraq, Ruqayyah J., Frias Boligan, Kayluz, Lewis, Bonnie J.B., Cen, Selena, Whetstone, Heather, Spirig, Rolf, Käsermann, Fabian, Campbell, Ian K., von Gunten, Stephan, Branch, Donald R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015763/
https://www.ncbi.nlm.nih.gov/pubmed/36696888
http://dx.doi.org/10.1159/000528780