LncRNA GAS5 suppresses TGF-β1-induced transformation of pulmonary pericytes into myofibroblasts by recruiting KDM5B and promoting H3K4me2/3 demethylation of the PDGFRα/β promoter

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a condition that may cause persistent pulmonary damage. The transformation of pericytes into myofibroblasts has been recognized as a key player during IPF progression. This study aimed to investigate the functions of lncRNA growth arrest-specific tr...

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Detalles Bibliográficos
Autores principales: Wang, Yichun, Chen, Diyu, Xie, Han, Zhou, Shuhua, Jia, Mingwang, He, Xiaobo, Guo, Feifei, Lai, Yihuan, Tang, Xiao Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015786/
https://www.ncbi.nlm.nih.gov/pubmed/36918759
http://dx.doi.org/10.1186/s10020-023-00620-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015786/
https://www.ncbi.nlm.nih.gov/pubmed/36918759
http://dx.doi.org/10.1186/s10020-023-00620-x

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