The role of NEDD4 related HECT-type E3 ubiquitin ligases in defective autophagy in cancer cells: molecular mechanisms and therapeutic perspectives

The homologous to the E6-AP carboxyl terminus (HECT)-type E3 ubiquitin ligases are the selective executers in the protein ubiquitination, playing a vital role in modulation of the protein function and stability. Evidence shows the regulatory role of HECT-type E3 ligases in various steps of the autop...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Shi, Shaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015828/
https://www.ncbi.nlm.nih.gov/pubmed/36918822
http://dx.doi.org/10.1186/s10020-023-00628-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015828/
https://www.ncbi.nlm.nih.gov/pubmed/36918822
http://dx.doi.org/10.1186/s10020-023-00628-3

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