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BCAT2 Shapes a Noninflamed Tumor Microenvironment and Induces Resistance to Anti‐PD‐1/PD‐L1 Immunotherapy by Negatively Regulating Proinflammatory Chemokines and Anticancer Immunity

To improve response rate of monotherapy of immune checkpoint blockade (ICB), it is necessary to find an emerging target in combination therapy. Through analyzing tumor microenvironment (TME)‐related indicators, it is validated that BCAT2 shapes a noninflamed TME in bladder cancer. The outcomes of mu...

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Detalles Bibliográficos
Autores principales: Cai, Zhiyong, Chen, Jinbo, Yu, Zhengzheng, Li, Huihuang, Liu, Zhi, Deng, Dingshan, Liu, Jinhui, Chen, Chunliang, Zhang, Chunyu, Ou, Zhenyu, Chen, Minfeng, Hu, Jiao, Zu, Xiongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015882/
https://www.ncbi.nlm.nih.gov/pubmed/36642843
http://dx.doi.org/10.1002/advs.202207155