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CCL5/CCR5-mediated peripheral inflammation exacerbates blood‒brain barrier disruption after intracerebral hemorrhage in mice

BACKGROUND: Owing to metabolic disequilibrium and immune suppression, intracerebral hemorrhage (ICH) patients are prone to infections; according to a recent global analysis of stroke cases, approximately 10 million new-onset ICH patients had experienced concurrent infection. However, the intrinsic m...

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Detalles Bibliográficos
Autores principales: Lin, Jie, Xu, Ya, Guo, Peiwen, Chen, Yù-Jié, Zhou, Jiru, Xia, Min, Tan, Binbin, Liu, Xin, Feng, Hua, Chen, Yujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015963/
https://www.ncbi.nlm.nih.gov/pubmed/36918921
http://dx.doi.org/10.1186/s12967-023-04044-3