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The Legacy of Infectious Disease Exposure on the Genomic Diversity of Indigenous Southern Mexicans

To characterize host risk factors for infectious disease in Mesoamerican populations, we interrogated 857,481 SNPs assayed using the Affymetrix 6.0 genotyping array for signatures of natural selection in immune response genes. We applied three statistical tests to identify signatures of natural sele...

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Detalles Bibliográficos
Autores principales: Garcia, Obed A, Arslanian, Kendall, Whorf, Daniel, Thariath, Serena, Shriver, Mark, Li, Jun Z, Bigham, Abigail W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016042/
https://www.ncbi.nlm.nih.gov/pubmed/36726304
http://dx.doi.org/10.1093/gbe/evad015