Genotypic effects of APOE-ε4 on resting-state connectivity in cognitively intact individuals support functional brain compensation

The investigation of resting-state functional connectivity (rsFC) in asymptomatic individuals at genetic risk for Alzheimer’s disease (AD) enables discovering the earliest brain alterations in preclinical stages of the disease. The APOE-ε4 variant is the major genetic risk factor for AD, and previou...

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Detalles Bibliográficos
Autores principales: Cacciaglia, Raffaele, Operto, Grégory, Falcón, Carles, de Echavarri-Gómez, José Maria González, Sánchez-Benavides, Gonzalo, Brugulat-Serrat, Anna, Milà-Alomà, Marta, Blennow, Kaj, Zetterberg, Henrik, Molinuevo, José Luis, Suárez-Calvet, Marc, Gispert, Juan Domingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016049/
https://www.ncbi.nlm.nih.gov/pubmed/35753703
http://dx.doi.org/10.1093/cercor/bhac239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016049/
https://www.ncbi.nlm.nih.gov/pubmed/35753703
http://dx.doi.org/10.1093/cercor/bhac239

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