LAL deficiency induced myeloid-derived suppressor cells as targets and biomarkers for lung cancer

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells in tumor microenvironment, which suppress antitumor immunity. Expansion of various MDSC subpopulations is closely associated with poor clinical outcomes in cancer. Lysosomal acid lipase (LAL) is a key enzyme...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Ting, Liu, Sheng, Hanna, Nasser H, Jalal, Shadia, Ding, Xinchun, Wan, Jun, Yan, Cong, Du, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016256/
https://www.ncbi.nlm.nih.gov/pubmed/36914206
http://dx.doi.org/10.1136/jitc-2022-006272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016256/
https://www.ncbi.nlm.nih.gov/pubmed/36914206
http://dx.doi.org/10.1136/jitc-2022-006272

Ejemplares similares