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Invasive margin tissue-resident macrophages of high CD163 expression impede responses to T cell-based immunotherapy

BACKGROUND: Primary and secondary resistance is a major hurdle in cancer immunotherapy. Therefore, a better understanding of the underlying mechanisms involved in immunotherapy resistance is of pivotal importance to improve therapy outcome. METHOD: Here, two mouse models with resistance against ther...

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Detalles Bibliográficos
Autores principales: van Elsas, Marit J, Labrie, Camilla, Etzerodt, Anders, Charoentong, Pornpimol, van Stigt Thans, Jordi J C, Van Hall, Thorbald, van der Burg, Sjoerd H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016286/
https://www.ncbi.nlm.nih.gov/pubmed/36914207
http://dx.doi.org/10.1136/jitc-2022-006433