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Autophagy controls mucus secretion from intestinal goblet cells by alleviating ER stress

Colonic goblet cells are specialized epithelial cells that secrete mucus to physically separate the host and its microbiota, thus preventing bacterial invasion and inflammation. How goblet cells control the amount of mucus they secrete is unclear. We found that constitutive activation of autophagy i...

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Detalles Bibliográficos
Autores principales: Naama, Maria, Telpaz, Shahar, Awad, Aya, Ben-Simon, Shira, Harshuk-Shabso, Sarina, Modilevsky, Sonia, Rubin, Elad, Sawaed, Jasmin, Zelik, Lilach, Zigdon, Mor, Asulin, Nofar, Turjeman, Sondra, Werbner, Michal, Wongkuna, Supapit, Feeney, Rachel, Schroeder, Bjoern O., Nyska, Abraham, Nuriel-Ohayon, Meital, Bel, Shai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016318/
https://www.ncbi.nlm.nih.gov/pubmed/36738733
http://dx.doi.org/10.1016/j.chom.2023.01.006