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Increased levels of immature and activated low density granulocytes and altered degradation of neutrophil extracellular traps in granulomatosis with polyangiitis

Granulomatosis with Polyangiitis (GPA) is a small vessel vasculitis typically associated with release of neutrophil extracellular traps (NETs) by activated neutrophils. In this study, we further aimed to investigate the contributions of neutrophils and NETs to the complex disease pathogenesis. We ch...

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Detalles Bibliográficos
Autores principales: Lipka, Spyridon, Ostendorf, Lennard, Schneider, Udo, Hiepe, Falk, Apel, Falko, Alexander, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016653/
https://www.ncbi.nlm.nih.gov/pubmed/36920946
http://dx.doi.org/10.1371/journal.pone.0282919