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The effect of a novel AQP4 facilitator, TGN-073, on glymphatic transport captured by diffusion MRI and DCE-MRI

The glymphatic system is a low resistance pathway, by which cerebrospinal fluid enters the brain parenchyma along perivascular spaces via AQP4 channels. It is hypothesised that the resulting convective flow of the interstitial fluid provides an efficient mechanism for the removal of waste toxins fro...

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Detalles Bibliográficos
Autores principales: Alghanimy, Alaa, Martin, Conor, Gallagher, Lindsay, Holmes, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016657/
https://www.ncbi.nlm.nih.gov/pubmed/36920936
http://dx.doi.org/10.1371/journal.pone.0282955