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The effect of a novel AQP4 facilitator, TGN-073, on glymphatic transport captured by diffusion MRI and DCE-MRI
The glymphatic system is a low resistance pathway, by which cerebrospinal fluid enters the brain parenchyma along perivascular spaces via AQP4 channels. It is hypothesised that the resulting convective flow of the interstitial fluid provides an efficient mechanism for the removal of waste toxins fro...
Autores principales: | Alghanimy, Alaa, Martin, Conor, Gallagher, Lindsay, Holmes, William M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016657/ https://www.ncbi.nlm.nih.gov/pubmed/36920936 http://dx.doi.org/10.1371/journal.pone.0282955 |
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