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B-cell epitope discovery: The first protein flexibility-based algorithm–Zika virus conserved epitope demonstration
Antibody-antigen interaction–at antigenic local environments called B-cell epitopes–is a prominent mechanism for neutralization of infection. Effective mimicry, and display, of B-cell epitopes is key to vaccine design. Here, a physical approach is evaluated for the discovery of epitopes which evolve...
Autores principales: | Biner, Daniel W., Grosch, Jason S., Ortoleva, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016673/ https://www.ncbi.nlm.nih.gov/pubmed/36920995 http://dx.doi.org/10.1371/journal.pone.0262321 |
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