Long-QT mutations in KCNE1 modulate the 17β-estradiol response of Kv7.1/KCNE1

Estradiol (17 [Formula: see text]-E2) is implicated in higher arrhythmia risk of women with congenital or acquired long-QT syndrome (LQTS) compared to men. However, the underlying mechanisms remain poorly understood, and little is known about the impact of LQTS-associated mutations. We show that 17...

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Detalles Bibliográficos
Autores principales: Erlandsdotter, Lisa-Marie, Giammarino, Lucilla, Halili, Azemine, Nikesjö, Johan, Gréen, Henrik, Odening, Katja E., Liin, Sara I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017040/
https://www.ncbi.nlm.nih.gov/pubmed/36921038
http://dx.doi.org/10.1126/sciadv.ade7109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017040/
https://www.ncbi.nlm.nih.gov/pubmed/36921038
http://dx.doi.org/10.1126/sciadv.ade7109

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