Diet-induced loss of adipose hexokinase 2 correlates with hyperglycemia

Chronically high blood glucose (hyperglycemia) leads to diabetes and fatty liver disease. Obesity is a major risk factor for hyperglycemia, but the underlying mechanism is unknown. Here, we show that a high-fat diet (HFD) in mice causes early loss of expression of the glycolytic enzyme Hexokinase 2...

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Detalles Bibliográficos
Autores principales: Shimobayashi, Mitsugu, Thomas, Amandine, Shetty, Sunil, Frei, Irina C, Wölnerhanssen, Bettina K, Weissenberger, Diana, Vandekeere, Anke, Planque, Mélanie, Dietz, Nikolaus, Ritz, Danilo, Meyer-Gerspach, Anne Christin, Maier, Timm, Hay, Nissim, Peterli, Ralph, Fendt, Sarah-Maria, Rohner, Nicolas, Hall, Michael N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017106/
https://www.ncbi.nlm.nih.gov/pubmed/36920797
http://dx.doi.org/10.7554/eLife.85103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017106/
https://www.ncbi.nlm.nih.gov/pubmed/36920797
http://dx.doi.org/10.7554/eLife.85103

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