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Pip5k1c Loss in Chondrocytes Causes Spontaneous Osteoarthritic Lesions in Aged Mice

Osteoarthritis (OA) is the most common degenerative joint disease affecting the older populations globally. Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (Pip5k1c), a lipid kinase catalyzing the synthesis of phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2), is involved in various c...

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Detalles Bibliográficos
Autores principales: Qu, Minghao, Chen, Mingjue, Gong, Weiyuan, Huo, Shaochuan, Yan, Qinnan, Yao, Qing, Lai, Yumei, Chen, Di, Wu, Xiaohao, Xiao, Guozhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017150/
https://www.ncbi.nlm.nih.gov/pubmed/37008048
http://dx.doi.org/10.14336/AD.2022.0828