Zn-dependent β-amyloid Aggregation and its Reversal by the Tetrapeptide HAEE

The pathogenesis of Alzheimer's disease (AD) is associated with the formation of cerebral amyloid plaques, the main components of which are the modified Aβ molecules as well as the metal ions. Aβ isomerized at Asp7 residue (isoD7-Aβ) is the most abundant isoform in amyloid plaques. We hypothesi...

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Detalles Bibliográficos
Autores principales: Mitkevich, Vladimir A, Barykin, Evgeny P, Eremina, Svetlana, Pani, Bibhusita, Katkova-Zhukotskaya, Olga, Polshakov, Vladimir I, Adzhubei, Alexei A, Kozin, Sergey A, Mironov, Alexander S, Makarov, Alexander A, Nudler, Evgeny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2023
Materias:
Short Comminication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017155/
https://www.ncbi.nlm.nih.gov/pubmed/37008059
http://dx.doi.org/10.14336/AD.2022.0827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017155/
https://www.ncbi.nlm.nih.gov/pubmed/37008059
http://dx.doi.org/10.14336/AD.2022.0827

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