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Microtubule nucleation from the fibrous corona by LIC1-pericentrin promotes chromosome congression

Error-free chromosome segregation in mitosis and meiosis relies on the assembly of a microtubule-based spindle that interacts with kinetochores to guide chromosomes to the cell equator before segregation in anaphase. Microtubules sprout from nucleation sites such as centrosomes, but kinetochores can...

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Detalles Bibliográficos
Autores principales: Wu, Jingchao, Larreategui-Aparicio, Ainhoa, Lambers, Maaike L.A., Bodor, Dani L., Klaasen, Sjoerd J., Tollenaar, Eveline, de Ruijter-Villani, Marta, Kops, Geert J.P.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017265/
https://www.ncbi.nlm.nih.gov/pubmed/36720222
http://dx.doi.org/10.1016/j.cub.2023.01.010