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Effects of selenium deficiency on biological results of X-ray and carbon-ion beam irradiation in mice

The impact of radiation-induced hydrogen peroxide (H(2)O(2)) on the biological effects of X-rays and carbon-ion beams was investigated using a selenium-deficient (SeD) mouse model. Selenium is the active center of glutathione peroxidase (GSH-Px), and SeD mice lack the ability to degrade H(2)O(2). Ma...

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Detalles Bibliográficos
Autores principales: Ueno, Megumi, Shibata, Sayaka, Nakanishi, Ikuo, Aoki, Ichio, Yamada, Ken-ichi, Matsumoto, Ken-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017320/
https://www.ncbi.nlm.nih.gov/pubmed/36936873
http://dx.doi.org/10.3164/jcbn.22-57