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ETV1 inhibition depressed M2 polarization of tumor-associated macrophage and cell process in gastrointestinal stromal tumor via down-regulating PDE3A

M2-type polarization of tumor associated-macrophage (TAM) is involved in the malignancy of gastrointestinal stromal tumor (GIST) progression. ETS variant 1 (ETV1) has been previously validated to regulate GIST pathogenesis. Our study intended to explore the role and mechanism of ETV1 in mediating th...

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Detalles Bibliográficos
Autores principales: Guo, Xueyan, Li, Yulong, Wan, Bingbing, Lv, Yifei, Wang, Xue, Liu, Guisheng, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017324/
https://www.ncbi.nlm.nih.gov/pubmed/36936869
http://dx.doi.org/10.3164/jcbn.22-47