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The clathrin adaptor complex-1 and Rab12 regulate post-golgi trafficking of WT epidermal growth factor receptor (EGFR)

The epidermal growth factor receptor (EGFR) plays important roles in cancer progression and is one of the major drug targets for targeted cancer therapy. Although fundamentally important, how newly synthesized EGFR is delivered to the cell surface to perform its cellular functions remains to be furt...

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Detalles Bibliográficos
Autores principales: Wang, Jinhui, Lau, Pik Ki, Li, Chun Wa, Guo, Yusong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017364/
https://www.ncbi.nlm.nih.gov/pubmed/36739948
http://dx.doi.org/10.1016/j.jbc.2023.102979