Spheromers reveal robust T cell responses to the Pfizer/BioNTech vaccine and attenuated peripheral CD8(+) T cell responses post SARS-CoV-2 infection

T cells are a critical component of the response to SARS-CoV-2, but their kinetics after infection and vaccination are insufficiently understood. Using “spheromer” peptide-MHC multimer reagents, we analyzed healthy subjects receiving two doses of the Pfizer/BioNTech BNT162b2 vaccine. Vaccination res...

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Detalles Bibliográficos
Autores principales: Gao, Fei, Mallajoysula, Vamsee, Arunachalam, Prabhu S., van der Ploeg, Kattria, Manohar, Monali, Röltgen, Katharina, Yang, Fan, Wirz, Oliver, Hoh, Ramona, Haraguchi, Emily, Lee, Ji-Yeun, Willis, Richard, Ramachandiran, Vasanthi, Li, Jiefu, Kathuria, Karan Raj, Li, Chunfeng, Lee, Alexandra S., Shah, Mihir M., Sindher, Sayantani B., Gonzalez, Joseph, Altman, John D., Wang, Taia T., Boyd, Scott D., Pulendran, Bali, Jagannathan, Prasanna, Nadeau, Kari C., Davis, Mark.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017386/
https://www.ncbi.nlm.nih.gov/pubmed/36996809
http://dx.doi.org/10.1016/j.immuni.2023.03.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017386/
https://www.ncbi.nlm.nih.gov/pubmed/36996809
http://dx.doi.org/10.1016/j.immuni.2023.03.005

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