Cargando…

BJTJ-1837, a novel FXI activation-blocking antibody

BACKGROUND: Factor (F)XI contributes to thrombosis development while it plays a limited role in normal hemostasis. FXI targeting has the potential for preventing and treating thrombosis with little bleeding risk. OBJECTIVES: The aim of this study was to develop novel antibody therapeutics against FX...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Xugang, Zhang, Jin, Du, Yanping, Liu, Xiao, Hu, Dongmei, Cao, Baohua, Gao, Hong, Wu, Yongguang, Zhou, Tianlin, Wu, Qimei, Huang, Qi, Yang, Changyong, Liao, Cheng, Zhang, Lianshan, Shen, Chenxi, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017418/
https://www.ncbi.nlm.nih.gov/pubmed/36936858
http://dx.doi.org/10.1016/j.rpth.2023.100067