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BJTJ-1837, a novel FXI activation-blocking antibody
BACKGROUND: Factor (F)XI contributes to thrombosis development while it plays a limited role in normal hemostasis. FXI targeting has the potential for preventing and treating thrombosis with little bleeding risk. OBJECTIVES: The aim of this study was to develop novel antibody therapeutics against FX...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017418/ https://www.ncbi.nlm.nih.gov/pubmed/36936858 http://dx.doi.org/10.1016/j.rpth.2023.100067 |