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BJTJ-1837, a novel FXI activation-blocking antibody

BACKGROUND: Factor (F)XI contributes to thrombosis development while it plays a limited role in normal hemostasis. FXI targeting has the potential for preventing and treating thrombosis with little bleeding risk. OBJECTIVES: The aim of this study was to develop novel antibody therapeutics against FX...

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Detalles Bibliográficos
Autores principales:	He, Xugang, Zhang, Jin, Du, Yanping, Liu, Xiao, Hu, Dongmei, Cao, Baohua, Gao, Hong, Wu, Yongguang, Zhou, Tianlin, Wu, Qimei, Huang, Qi, Yang, Changyong, Liao, Cheng, Zhang, Lianshan, Shen, Chenxi, Wang, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017418/ https://www.ncbi.nlm.nih.gov/pubmed/36936858 http://dx.doi.org/10.1016/j.rpth.2023.100067

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