Modeling intercellular communication in tissues using spatial graphs of cells

Models of intercellular communication in tissues are based on molecular profiles of dissociated cells, are limited to receptor–ligand signaling and ignore spatial proximity in situ. We present node-centric expression modeling, a method based on graph neural networks that estimates the effects of nic...

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Detalles Bibliográficos
Autores principales: Fischer, David S., Schaar, Anna C., Theis, Fabian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017508/
https://www.ncbi.nlm.nih.gov/pubmed/36302986
http://dx.doi.org/10.1038/s41587-022-01467-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017508/
https://www.ncbi.nlm.nih.gov/pubmed/36302986
http://dx.doi.org/10.1038/s41587-022-01467-z

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