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Modeling intercellular communication in tissues using spatial graphs of cells
Models of intercellular communication in tissues are based on molecular profiles of dissociated cells, are limited to receptor–ligand signaling and ignore spatial proximity in situ. We present node-centric expression modeling, a method based on graph neural networks that estimates the effects of nic...
Autores principales: | Fischer, David S., Schaar, Anna C., Theis, Fabian J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017508/ https://www.ncbi.nlm.nih.gov/pubmed/36302986 http://dx.doi.org/10.1038/s41587-022-01467-z |
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