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Role of allopregnanolone-mediated γ-aminobutyric acid A receptor sensitivity in the pathogenesis of premenstrual dysphoric disorder: Toward precise targets for translational medicine and drug development

Premenstrual dysphoric disorder (PMDD) can be conceptualized as a disorder of suboptimal sensitivity to neuroactive steroid hormones. Its core symptoms (emotional instability, irritability, depression, and anxiety) are related to the increase of stress sensitivity due to the fluctuation of hormone l...

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Detalles Bibliográficos
Autores principales: Gao, Qian, Sun, Wei, Wang, Yue-Rui, Li, Zi-Fa, Zhao, Feng, Geng, Xi-Wen, Xu, Kai-Yong, Chen, Dan, Liu, Kun, Xing, Ying, Liu, Wei, Wei, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017536/
https://www.ncbi.nlm.nih.gov/pubmed/36937732
http://dx.doi.org/10.3389/fpsyt.2023.1140796