Efavirenz restored NMDA receptor dysfunction and inhibited epileptic seizures in GluN2A/Grin2a mutant mice

INTRODUCTION: N-methyl-D-aspartate receptor (NMDAR) is one of the main receptor of the excitatory neurotransmitter glutamate in the brain, which is the key determinant of the excitatory/inhibitory balance of neural network. GluN2A/GRIN2A is one of the subunits of NMDAR and plays an important role in...

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Detalles Bibliográficos
Autores principales: Zhao, Teng, Zhong, Rui, Zhang, Xinyue, Li, Guangjian, Zhou, Chunkui, Fang, Shaokuan, Ding, Ying, Lin, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017539/
https://www.ncbi.nlm.nih.gov/pubmed/36937661
http://dx.doi.org/10.3389/fnins.2023.1086462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017539/
https://www.ncbi.nlm.nih.gov/pubmed/36937661
http://dx.doi.org/10.3389/fnins.2023.1086462

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