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DNA methyltransferase inhibition induces dynamic gene expression changes in lung CD4(+) T cells of neonatal mice with E. coli pneumonia
Bacterial pulmonary infections are a major cause of morbidity and mortality in neonates, with less severity in older children. Previous studies demonstrated that the DNA of CD4(+) T cells in the mouse lung, whose primary responsibility is to coordinate the immune response to foreign pathogens, is di...
Autores principales: | Michki, Nigel S., Ndeh, Roland, Helmin, Kathryn A., Singer, Benjamin D., McGrath-Morrow, Sharon A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017701/ https://www.ncbi.nlm.nih.gov/pubmed/36922640 http://dx.doi.org/10.1038/s41598-023-31285-5 |
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