Revisiting the inhibitory potential of protein kinase inhibitors against NEK7 protein via comprehensive computational investigations

The NEK7 protein is required for spindle formation, cell division, and the activation of the NLRP3 inflammasome receptor. The aberrant expression of NEK7 has been implicated to the growth of metastasis and severe inflammatory conditions like rheumatoid arthritis, liver cirrhosis, and gout. An emerge...

Descripción completa

Detalles Bibliográficos
Autores principales: Ejaz, Syeda Abida, Aziz, Mubashir, Zafar, Zeenat, Akhtar, Naveed, Ogaly, Hanan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017757/
https://www.ncbi.nlm.nih.gov/pubmed/36922575
http://dx.doi.org/10.1038/s41598-023-31499-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017757/
https://www.ncbi.nlm.nih.gov/pubmed/36922575
http://dx.doi.org/10.1038/s41598-023-31499-7

Ejemplares similares